Shatavarins (steroidal saponins): (1) increase prolactin secretion from anterior pituitary, possibly by modulating dopaminergic tone (dopamine inhibits prolactin; shatavari may reduce dopamine's inhibitory effect); (2) phytoestrogenic, bind ERα and ERβ with moderate affinity, providing mild estrogenic support for reproductive tissues; (3) adaptogenic, modulate HPA axis cortisol response; (4) gastroprotective, increase gastric mucus secretion and prostaglandin E2 production (protective), while reducing acid secretion; (5) antioxidant, direct free radical scavenging and SOD enhancement; (6) immunomodulatory, enhance macrophage activity and IL-1 production.
Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:
Not medical advice. Based on published clinical research and systematic reviews.