Arjunolic acid and related triterpene saponins: (1) positive inotropic effect, strengthen cardiac muscle contraction (similar to but weaker than digitalis, without the toxicity); (2) coronary vasodilation, improve blood flow to heart muscle; (3) myocardial antioxidant, specifically accumulate in cardiac tissue and reduce oxidative damage; (4) endothelial nitric oxide enhancement, improve eNOS expression and NO-mediated vasodilation; (5) anti-atherosclerotic, reduce LDL oxidation and foam cell formation. The mechanism profile makes arjuna a broad-spectrum cardiac support herb.
Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:
Not medical advice. Based on published clinical research and systematic reviews.