Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD
Apigenin
MODERATE EVIDENCEBotanicalLast updated
AVELOR SUMMARY
The flavonoid in chamomile and parsley that inhibits CD38 (the NAD+-consuming enzyme). By blocking CD38, apigenin may preserve NAD+ levels — relevant for aging. Also anxiolytic via GABA-A modulation and aromatase inhibitor. Huberman popularized it for sleep.
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*Reviewed by the Dose AI Research Team and Clinical Advisory Board*
*Last updated: 2026-04-06*
Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:
Not medical advice. Based on published clinical research and systematic reviews.