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What works, what does not, and what is dangerous. Reviewed by theAvelor Research Team.
Effective Dose
600-800mcg daily, start preconception
Prevents neural tube defects. Methylfolate preferred if MTHFR variant.
PMID: 26350239Effective Dose
27mg elemental iron daily
Prevents maternal anemia. Bisglycinate is gentler on GI than ferrous sulfate.
PMID: 31995626Effective Dose
200-300mg DHA daily
Fetal brain and eye development. Algal oil is a clean vegan option.
PMID: 28915430Effective Dose
450-550mg daily
Critical for fetal brain development. Most prenatals contain none.
PMID: 28724643Effective Dose
220mcg daily
Prevents fetal neurodevelopmental deficits. Do not megadose.
PMID: 22155974Effective Dose
1000-2000 IU to target 40-60 ng/mL
Lowers risk of preeclampsia, gestational diabetes, preterm birth.
PMID: 28359097Effective Dose
250mg-1g/day
Safe, effective for morning sickness. Comparable to some prescription antiemetics.
PMID: 24642205High-Dose Vitamin E
No benefit for miscarriage prevention. Higher doses linked to adverse outcomes.
Raspberry Leaf Tea
Popular for "easier labor" but evidence is thin and inconsistent.
Colloidal Silver
Zero medical benefit. Crosses placenta and can cause argyria in infant.
Herbal "Uterus Tonics"
Most have no safety data in pregnancy. Avoid.
Teratogenic. Use beta-carotene form instead.
FDA miscarriage warning.
Linked to adverse birth outcomes at >400 IU.
Linked to preterm birth. Avoid entirely.
Cardiotoxic to fetus. Do NOT use.
Increased bleeding risk, possible uterine stimulation.
Hepatotoxicity risk. Not considered safe in pregnancy.