Evidence-Based Supplement Protocols

Supplements for focus, attention, and cognitive performance, from the existing ADHD protocol library.

Supplements for calm, stress resilience, and mood stability from the existing anxiety protocol library.

Treatment tiers, lab targets, and progress tracking for hair recovery from the existing protocol hub.

Lower stress, improve sleep, restore balance

KSM-66 Ashwagandha has been shown in multiple RCTs to reduce serum cortisol by 23-30% over 8 weeks (Chandrasekhar et al., 2012). Magnesium glycinate s

Replenish what weight loss meds deplete

Research shows GLP-1 RA users are at elevated risk for B12 deficiency (up to 22% in long-term users, Aroda et al., 2016), iron depletion, and calcium/

Fall asleep faster, sleep deeper, wake refreshed

Magnesium glycinate enhances GABA activity and has been shown to improve sleep quality in RCTs (Abbasi et al., 2012). L-theanine promotes alpha wave r

Sharpen cognition, clear brain fog, sustain attention

Alpha-GPC increases acetylcholine, the neurotransmitter essential for memory and focus (Traini et al., 2013). Omega-3 DHA comprises 40% of brain polyu

Train harder, recover faster, build more

Creatine monohydrate increases phosphocreatine stores, improving high-intensity performance by 10-15% and lean mass gains (Kreider et al., 2017). Coll

Phase-matched nutrients for hormonal balance

Magnesium supplementation reduces PMS symptoms by 34% (Quaranta et al., 2007). Calcium at 1200mg/day reduces PMS severity by 48% (Thys-Jacobs et al.,

Evidence-based support for low mood and emotional resilience

Saffron extract (28mg/day) showed antidepressant effects equivalent to fluoxetine 20mg in a 2013 meta-analysis of 5 RCTs (Hausenblas et al.). EPA-domi

Clear the fog, sharpen memory, sustain deep work

Creatine monohydrate improves cognitive performance by 10-15% in sleep-deprived and cognitively demanding conditions (Avgerinos et al., 2018 meta-anal

Hot flash reduction, bone protection, mood stability

Black cohosh reduces hot flash frequency by 26% in a Cochrane review (Leach & Moore, 2012). Saffron 28mg/day significantly reduces hot flash frequency

Magnesium · Theanine · Apigenin — the wind-down stack

Magnesium glycinate is the chelated form with the cleanest absorption profile and zero GI burden — supports GABA-A receptor function and lowers nightt

L-Tyrosine · Caffeine + Theanine · Alpha-GPC — the deep-work stack

L-Tyrosine is the precursor to dopamine and norepinephrine — supplementation under cognitive stress preserves working memory and reaction time (Jongke

NMN · Resveratrol · Vitamin D + K2 — the foundational stack

NMN (nicotinamide mononucleotide) is the direct precursor to NAD+, which declines ~50% between ages 40 and 60 — supplementation restores NAD+ to youth