Is White Willow Bark safe to take daily?

White Willow Bark is rated "Generally Safe" based on clinical evidence. Always consult your healthcare provider before starting any supplement.

Ingredient Research

Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD

White Willow Bark

Creator: Avelor Research Team
Published: 2026-04-01

MODERATE EVIDENCESupplementLast updated

AVELOR SUMMARY

White willow bark is the original aspirin, it contains salicin, which the body converts to salicylic acid (aspirin is acetylsalicylic acid). A 2001 Cochrane review found willow bark extract (240mg salicin/day) reduced low back pain by 39%, comparable to rofecoxib (Vioxx). Unlike aspirin, willow bark causes LESS GI irritation because salicin is converted to salicylic acid in the liver (not the stomach). Dose: 120-240mg salicin/day. Assalix® is the standardized extract. Same antiplatelet and drug interaction cautions as aspirin. --- *Reviewed by the Avelor Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*

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Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:

Not medical advice. Based on published clinical research and systematic reviews.

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