Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD
Vitamin B9 — See folic-acid.md and methyl-folate.md
MODERATE EVIDENCEVitaminLast updated
AVELOR SUMMARY
and methyl-folate.md. Two forms: folic acid (synthetic, must be converted by MTHFR) and methylfolate/5-MTHF (active, bypasses MTHFR). 40% of population has MTHFR C677T variant with reduced conversion. Neural tube defect prevention: 400-800μg/day pre-conception.
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*Reviewed by the Dose AI Research Team and Clinical Advisory Board*
*Last updated: 2026-04-06*
Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:
Not medical advice. Based on published clinical research and systematic reviews.