Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD
Valine
MODERATE EVIDENCESupplementLast updated
AVELOR SUMMARY
Valine is the least-studied BCAA. While leucine activates mTOR and isoleucine activates GLUT4, valine's unique metabolic role is glycogen sparing during exercise. for BCAA overview. Individual valine supplementation is rarely warranted — BCAAs or EAAs are preferred.
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*Reviewed by the Dose AI Research Team and Clinical Advisory Board*
*Last updated: 2026-04-06*
Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:
Not medical advice. Based on published clinical research and systematic reviews.