Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD
Sorghum Extract
MODERATE EVIDENCESupplementLast updated
AVELOR SUMMARY
Dynamine® (methylliberine) from sorghum is a purine alkaloid structurally similar to caffeine and theacrine but with FASTER onset and SHORTER duration, 'the espresso shot of nootropics.' Acts on adenosine and dopamine receptors. Does NOT increase BP or HR in preliminary data. Onset: 15-30 minutes. Duration: 1-3 hours (vs caffeine's 5-6 hours). Dose: 100-200mg. No tolerance development reported. Often stacked with TeaCrine® for extended duration.
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*Reviewed by the Avelor Research Team and Clinical Advisory Board*
*Last updated: 2026-04-06*
Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:
Not medical advice. Based on published clinical research and systematic reviews.