Is Sorghum Extract safe to take daily?

Sorghum Extract is rated "Generally Safe" based on clinical evidence. Always consult your healthcare provider before starting any supplement.

Ingredient Research

Graded against 178,763 supplements + 140 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD

Sorghum Extract

Creator: Avelor Research Team
Published: 2026-04-01

MODERATE EVIDENCESupplementLast updated

AVELOR SUMMARY

Dynamine® (methylliberine) from sorghum is a purine alkaloid structurally similar to caffeine and theacrine but with FASTER onset and SHORTER duration, 'the espresso shot of nootropics.' Acts on adenosine and dopamine receptors. Does NOT increase BP or HR in preliminary data. Onset: 15-30 minutes. Duration: 1-3 hours (vs caffeine's 5-6 hours). Dose: 100-200mg. No tolerance development reported. Often stacked with TeaCrine® for extended duration. --- *Reviewed by the Avelor Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*

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Independently graded against 178,763 indexed supplements with 140 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:

Not medical advice. Based on published clinical research and systematic reviews.

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