Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD
Silibinin / Silymarin
MODERATE EVIDENCESupplementLast updated
AVELOR SUMMARY
Silibinin is the most active component of milk thistle's silymarin complex. 420-600mg/day silymarin for liver protection. IV silibinin (Legalon SIL®) is the ONLY approved treatment for Amanita mushroom (death cap) poisoning — it blocks hepatocyte toxin uptake.
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*Reviewed by the Dose AI Research Team and Clinical Advisory Board*
*Last updated: 2026-04-06*
Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:
Not medical advice. Based on published clinical research and systematic reviews.