Saponins are amphipathic glycosides found in ginseng, tribulus, astragalus, yucca, soapwort, etc. They foam in water (natural soap).
Biological activities: immune modulation (vaccine adjuvants like QS-21), cholesterol binding (reduced absorption), cytotoxicity to cancer cells (membrane disruption), and adaptogenic effects.
NOT a single compound, saponin activities vary enormously by source plant. Anti-nutrient effect at high doses (bind minerals, irritate gut).
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*Reviewed by the Avelor Research Team and Clinical Advisory Board*
*Last updated: 2026-04-06*