Is Sage safe to take daily?

Sage is rated "Generally Safe" based on clinical evidence. Always consult your healthcare provider before starting any supplement.

Ingredient Research

Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD

Sage

Creator: Avelor Research Team
Published: 2026-04-01

MODERATE EVIDENCESupplementLast updated

AVELOR SUMMARY

Sage contains rosmarinic acid and carnosic acid with cholinesterase inhibitory activity, the SAME mechanism as Alzheimer's drugs (donepezil, galantamine). A 2003 study found 333mg/day sage extract improved word recall and attention in healthy young adults. Also reduces hot flashes by 60% (phytoestrogenic) and lowers blood sugar. The essential oil should NOT be ingested (thujone content, neurotoxic). Use dried leaf extract or standardized capsules. Dose: 300-600mg/day. --- *Reviewed by the Avelor Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*

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Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:

Not medical advice. Based on published clinical research and systematic reviews.

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