Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD
Saffron
MODERATE EVIDENCESupplementLast updated
AVELOR SUMMARY
Crocin and safranal — antidepressant activity comparable to fluoxetine and imipramine in 6 RCTs. 30mg/day. Also improves sexual dysfunction and reduces PMS. Affron® is the branded extract. The most expensive spice in the world (,000-10,000/kg).
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*Reviewed by the Dose AI Research Team and Clinical Advisory Board*
*Last updated: 2026-04-06*
Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:
Not medical advice. Based on published clinical research and systematic reviews.