Is Royal Jelly safe to take daily?

Royal Jelly is rated "Generally Safe" based on clinical evidence. Always consult your healthcare provider before starting any supplement.

Ingredient Research

Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD

Royal Jelly

Creator: Avelor Research Team
Published: 2026-04-01

MODERATE EVIDENCESupplementLast updated

AVELOR SUMMARY

Royal jelly is the exclusive food of queen bees, composed of proteins (MRJPs), fatty acids (10-HDA), and royalactin. 10-HDA (10-hydroxy-2-decenoic acid) is the unique fatty acid with anti-inflammatory and HDAC inhibitory activity. Clinical evidence: royal jelly (3g/day, 6 months) improved total cholesterol by 11% and LDL by 4% in a 2007 Japanese study. Also improved menopausal symptoms and glucose tolerance. ALLERGY RISK: multiple case reports of fatal anaphylaxis in atopic individuals. Bee allergy screening recommended. Not recommended for anyone with bee/pollen allergies. --- *Reviewed by the Avelor Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*

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Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:

Not medical advice. Based on published clinical research and systematic reviews.

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