Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD
Pantethine
MODERATE EVIDENCESupplementLast updated
AVELOR SUMMARY
Pantethine is the active form of pantothenic acid (B5) — a CoA precursor. 600-900mg/day reduced total cholesterol by 11% and LDL by 13% in multiple studies. The mechanism: pantethine increases CoA availability in the liver, enhancing fatty acid oxidation. It's distinct from pantothenic acid (inactive until converted). Pantesin® is the branded form. Better for cholesterol than regular B5.
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*Reviewed by the Dose AI Research Team and Clinical Advisory Board*
*Last updated: 2026-04-06*
Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:
Not medical advice. Based on published clinical research and systematic reviews.