Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD
Isoleucine
MODERATE EVIDENCESupplementLast updated
AVELOR SUMMARY
Isoleucine is the BCAA responsible for glucose uptake — it activates GLUT4 translocation to muscle cell membranes independently of insulin. Less studied individually than leucine (the mTOR activator). Relevant for: blood sugar management, muscle glucose delivery during exercise. for BCAA overview.
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*Reviewed by the Dose AI Research Team and Clinical Advisory Board*
*Last updated: 2026-04-06*
Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:
Not medical advice. Based on published clinical research and systematic reviews.