Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD
I3C
MODERATE EVIDENCESupplementLast updated
AVELOR SUMMARY
Cruciferous vegetable compound that shifts estrogen metabolism toward protective 2-OHE1. DIM (diindolylmethane) is preferred over I3C for supplementation — more predictable conversion, avoids ICZ (AhR agonist) formation in stomach.
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*Reviewed by the Dose AI Research Team and Clinical Advisory Board*
*Last updated: 2026-04-06*
Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:
Not medical advice. Based on published clinical research and systematic reviews.