Dong quai contains three pharmacologically active compound classes: (1) phthalides (ligustilide, butylphthalide), smooth muscle relaxants that may relieve menstrual cramps; (2) coumarins, natural blood thinners that inhibit platelet aggregation; and (3) ferulic acid, an anti-inflammatory and antioxidant. In TCM theory, it "nourishes blood" and "invigorates circulation." The coumarin content is the primary safety concern, it genuinely affects clotting.
Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:
Not medical advice. Based on published clinical research and systematic reviews.