Dong quai contains three pharmacologically active compound classes: (1) phthalides (ligustilide, butylphthalide), smooth muscle relaxants that may relieve menstrual cramps; (2) coumarins, natural blood thinners that inhibit platelet aggregation; and (3) ferulic acid, an anti-inflammatory and antioxidant. In TCM theory, it "nourishes blood" and "invigorates circulation." The coumarin content is the primary safety concern, it genuinely affects clotting.
Independently graded against 178,763 indexed supplements and 757 reviewed supplement and medication pairs, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:
Not medical advice. Based on published clinical research and systematic reviews.