Essential nutrient — 90% of Americans are deficient. Required for: acetylcholine synthesis, phosphatidylcholine (cell membranes), VLDL secretion (liver fat export), and methylation (methyl donor). Adequate intake: 550mg/day men, 425mg/day women. Eggs are the richest dietary source (147mg per egg). Forms: choline bitartrate (cheapest), CDP-choline/citicoline (brain), Alpha-GPC (brain+GH). --- *Reviewed by the Dose AI Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*
Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:
Not medical advice. Based on published clinical research and systematic reviews.