What works, what does not, and what is dangerous. Reviewed by theAvelor Research Team.
Effective Dose
200-400mg daily, often with 100mg caffeine
Improves attention and reaction time, especially combined with caffeine. Calm focus without sedation.
PMID: 18681988Effective Dose
1-2g EPA-dominant/day
Modest improvements in ADHD symptoms in children. EPA-dominant formulas outperform DHA-dominant.
PMID: 28741625Effective Dose
200-400mg elemental Mg
Correcting deficiency reduces hyperactivity in kids with low magnesium.
PMID: 9368236Effective Dose
15-65mg elemental iron
ADHD children with ferritin <30 ng/mL often show improvement with iron repletion. Do not supplement without a ferritin test.
PMID: 15583094Effective Dose
40-200mg
Modest focus benefit. Stack with L-theanine for smoother effect.
PMID: 18681988Ginkgo Biloba
Inconsistent evidence for cognition or ADHD. Often marketed as a focus aid but studies are mixed at best.
Phosphatidylserine
Weak signal in ADHD trials. Benefits, if any, are small and short-lived.
Nootropic Blends
Most "brain" blends under-dose effective ingredients and hide doses in proprietary blends.
Prevagen (apoaequorin)
No credible evidence. FTC sued the maker for deceptive marketing.
FDA miscarriage warning. Do NOT take if pregnant or trying.
Independent tests found <2% of labeled dose. Low-quality sources are common.
Compounded heart rate and blood pressure elevation.
Over-stimulation, insomnia, blood pressure spikes.